4kct

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==Pyruvate kinase (PYK) from Trypanosoma brucei soaked with Oxaloacetate==
==Pyruvate kinase (PYK) from Trypanosoma brucei soaked with Oxaloacetate==
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<StructureSection load='4kct' size='340' side='right' caption='[[4kct]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4kct' size='340' side='right'caption='[[4kct]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kct]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KCT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kct]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KCT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kcu|4kcu]], [[4kcv|4kcv]], [[4kcw|4kcw]], [[4hyv|4hyv]], [[4hyw|4hyw]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PYK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kct OCA], [https://pdbe.org/4kct PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kct RCSB], [https://www.ebi.ac.uk/pdbsum/4kct PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kct ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kct OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kct RCSB], [http://www.ebi.ac.uk/pdbsum/4kct PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KPYK1_TRYBB KPYK1_TRYBB]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4kct" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Pyruvate Kinase|Pyruvate Kinase]]
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*[[Pyruvate kinase 3D structures|Pyruvate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pyruvate kinase]]
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[[Category: Large Structures]]
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[[Category: Trybb]]
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[[Category: Trypanosoma brucei brucei]]
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[[Category: Fothergill-Gilmore, L A]]
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[[Category: Fothergill-Gilmore LA]]
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[[Category: McNae, I W]]
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[[Category: McNae IW]]
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[[Category: Michels, P A.M]]
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[[Category: Michels PAM]]
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[[Category: Morgan, H P]]
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[[Category: Morgan HP]]
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[[Category: Walkinshaw, M D]]
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[[Category: Walkinshaw MD]]
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[[Category: Zhong, W]]
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[[Category: Zhong W]]
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[[Category: Decarboxylase]]
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[[Category: Transferase]]
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Current revision

Pyruvate kinase (PYK) from Trypanosoma brucei soaked with Oxaloacetate

PDB ID 4kct

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