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4eec
From Proteopedia
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==Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934.== | ==Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934.== | ||
| - | <StructureSection load='4eec' size='340' side='right' caption='[[4eec]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='4eec' size='340' side='right'caption='[[4eec]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4eec]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4eec]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_toyocaensis Streptomyces toyocaensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EEC FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0UZ:(2R)-AMINO(3-CHLORO-4-HYDROXYPHENYL)ETHANOIC+ACID'>0UZ</scene>, <scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=3MY:3-CHLORO-D-TYROSINE'>3MY</scene>, <scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eec OCA], [https://pdbe.org/4eec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eec RCSB], [https://www.ebi.ac.uk/pdbsum/4eec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eec ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/STAL_STRTO STAL_STRTO] Catalyzes the sulfonation of desulfo-A47934, the final step of A47934 biosynthesis. Has also weak activity in vitro with teicoplanin aglycone and teicoplanin.<ref>PMID:16492565</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Streptomyces toyocaensis]] | [[Category: Streptomyces toyocaensis]] | ||
| - | [[Category: Cygler | + | [[Category: Cygler M]] |
| - | [[Category: Shi | + | [[Category: Shi R]] |
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Current revision
Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934.
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