2h71

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[[Image:2h71.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of Thioredoxin Mutant D47E in Hexagonal (p61) Space Group==
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|PDB= 2h71 |SIZE=350|CAPTION= <scene name='initialview01'>2h71</scene>, resolution 2.20&Aring;
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<StructureSection load='2h71' size='340' side='right'caption='[[2h71]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
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<table><tr><td colspan='2'>[[2h71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H71 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Lyase Lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.7.1.4. 4.7.1.4.]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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|GENE= trxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h71 OCA], [https://pdbe.org/2h71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h71 RCSB], [https://www.ebi.ac.uk/pdbsum/2h71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h71 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/2h71_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h71 ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of Thioredoxin Mutant D47E in Hexagonal (p61) Space Group'''
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==See Also==
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*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2H71 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H71 OCA].
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Lyase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Gavira JA]]
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[[Category: Gavira, J A.]]
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[[Category: Godoy-Ruiz R]]
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[[Category: Godoy-Ruiz, R.]]
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[[Category: Ibarra-Molero B]]
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[[Category: Ibarra-Molero, B.]]
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[[Category: Sanchez-Ruiz JM]]
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[[Category: Sanchez-Ruiz, J M.]]
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[[Category: MPD]]
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[[Category: alpha beta]]
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[[Category: electron transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:13:25 2008''
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Current revision

Crystal Structure of Thioredoxin Mutant D47E in Hexagonal (p61) Space Group

PDB ID 2h71

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