2hcu

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[[Image:2hcu.gif|left|200px]]
 
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{{Structure
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==Crystal Structure Of Smu.1381 (or LeuD) from Streptococcus Mutans==
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|PDB= 2hcu |SIZE=350|CAPTION= <scene name='initialview01'>2hcu</scene>, resolution 2.10&Aring;
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<StructureSection load='2hcu' size='340' side='right'caption='[[2hcu]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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<table><tr><td colspan='2'>[[2hcu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HCU FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/3-isopropylmalate_dehydratase 3-isopropylmalate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.33 4.2.1.33]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hcu OCA], [https://pdbe.org/2hcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hcu RCSB], [https://www.ebi.ac.uk/pdbsum/2hcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hcu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LEUD_STRMU LEUD_STRMU] Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hc/2hcu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hcu ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure Of Smu.1381 (or LeuD) from Streptococcus Mutans'''
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==See Also==
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*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
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*[[Isopropylmalate isomerase|Isopropylmalate isomerase]]
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==About this Structure==
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__TOC__
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2HCU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HCU OCA].
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</StructureSection>
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[[Category: 3-isopropylmalate dehydratase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Streptococcus mutans]]
[[Category: Streptococcus mutans]]
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[[Category: Dong, Y H.]]
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[[Category: Dong YH]]
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[[Category: Gao, Z Q.]]
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[[Category: Gao ZQ]]
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[[Category: Hou, H F.]]
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[[Category: Hou HF]]
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[[Category: Li, L F.]]
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[[Category: Li LF]]
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[[Category: Liang, Y H.]]
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[[Category: Liang YH]]
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[[Category: Su, X D.]]
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[[Category: Su XD]]
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[[Category: SO4]]
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[[Category: beta barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:15:30 2008''
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Current revision

Crystal Structure Of Smu.1381 (or LeuD) from Streptococcus Mutans

PDB ID 2hcu

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