4q12
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of a putative uncharacterized protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis bound to uridine diphosphate== | ==Crystal structure of a putative uncharacterized protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis bound to uridine diphosphate== | ||
| - | <StructureSection load='4q12' size='340' side='right' caption='[[4q12]], [[Resolution|resolution]] 2.85Å' scene=''> | + | <StructureSection load='4q12' size='340' side='right'caption='[[4q12]], [[Resolution|resolution]] 2.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4q12]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4q12]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q12 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q12 OCA], [https://pdbe.org/4q12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q12 RCSB], [https://www.ebi.ac.uk/pdbsum/4q12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q12 ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SUGFT_MYCTU SUGFT_MYCTU] Sugar N-formyltransferase that catalyzes the conversion of dTDP-4-amino-4,6-dideoxyglucose into dTDP-4-formamido-4,6-dideoxyglucose using N(10)-formyltetrahydrofolate as the carbon source (PubMed:28665588). Plays a role in virulence (PubMed:12368431). Has no activity on dTDP-3-amino-3,6-dideoxyglucose, dTDP-3-amino-3,6-dideoxygalactose, UDP-4-amino-4-deoxyarabinose, and GDP-4-amino-4,6-dideoxymannose (PubMed:28665588).<ref>PMID:12368431</ref> <ref>PMID:28665588</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
| - | [[Category: Cell wall biogenesis]] | ||
| - | [[Category: National institute for allergy and infectious disease]] | ||
| - | [[Category: National institute of allergy and infectious disease]] | ||
| - | [[Category: Niaid]] | ||
| - | [[Category: Ssgcid]] | ||
| - | [[Category: Sugar formyl transferase]] | ||
| - | [[Category: Transferase]] | ||
Current revision
Crystal structure of a putative uncharacterized protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis bound to uridine diphosphate
| |||||||||||
