3zh4

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==crystal structure of S. pneumoniae Hungary 19A MurA1 in complex with citrate==
==crystal structure of S. pneumoniae Hungary 19A MurA1 in complex with citrate==
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<StructureSection load='3zh4' size='340' side='right' caption='[[3zh4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='3zh4' size='340' side='right'caption='[[3zh4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zh4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZH4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zh4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZH4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zh4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zh4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zh4 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zh4 OCA], [https://pdbe.org/3zh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zh4 RCSB], [https://www.ebi.ac.uk/pdbsum/3zh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zh4 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MURA1_STRPI MURA1_STRPI] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity). Target for the antibiotic fosfomycin.[HAMAP-Rule:MF_00111]<ref>PMID:23571543</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3zh4" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Enoylpyruvate transferase|Enoylpyruvate transferase]]
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*[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
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[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
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[[Category: Gutierrez-Fernandez J]]
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[[Category: Gutierrez-Fernandez, J]]
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[[Category: Hermoso JA]]
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[[Category: Hermoso, J A]]
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[[Category: Mura]]
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[[Category: Transferase]]
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crystal structure of S. pneumoniae Hungary 19A MurA1 in complex with citrate

PDB ID 3zh4

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