This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2huy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:51, 13 August 2008) (edit) (undo)
(Redirecting to 3c7i)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2huy.gif|left|200px]]
+
#REDIRECT [[3c7i]] This PDB entry is obsolete and replaced by 3c7i
-
 
+
-
{{Structure
+
-
|PDB= 2huy |SIZE=350|CAPTION= <scene name='initialview01'>2huy</scene>, resolution 1.700&Aring;
+
-
|SITE=
+
-
|LIGAND= <scene name='pdbligand=YVN:N-({(1R,2R,3S)-2-[(METHYLAMINO)CARBONYL]-3-[4-(PHOSPHONOOXY)PHENYL]CYCLOPROPYL}CARBONYL)-L-VALYL-L-ASPARTAMIDE'>YVN</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
+
-
|ACTIVITY=
+
-
|GENE= GRB2, ASH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
-
}}
+
-
 
+
-
'''X-ray crystal structure of the complex between the Grb2-SH2 domain and a flexible ligand, fpYVN.'''
+
-
 
+
-
 
+
-
==Disease==
+
-
Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=100790 100790]], Haddad syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=100790 100790]]
+
-
 
+
-
==About this Structure==
+
-
2HUY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HUY OCA].
+
-
 
+
-
==Reference==
+
-
Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17001728 17001728]
+
-
[[Category: Homo sapiens]]
+
-
[[Category: Single protein]]
+
-
[[Category: Benfield, A P.]]
+
-
[[Category: Martin, S F.]]
+
-
[[Category: FMT]]
+
-
[[Category: YVN]]
+
-
[[Category: constrained]]
+
-
[[Category: entropy]]
+
-
[[Category: flexible]]
+
-
[[Category: grb2-sh2]]
+
-
[[Category: ligand preorganization]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:21:54 2008''
+

Current revision

  1. REDIRECT 3c7i This PDB entry is obsolete and replaced by 3c7i

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2huy"
Personal tools