1oba

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==MULTIMODULAR PNEUMOCOCCAL CELL WALL ENDOLYSIN FROM PHAGE CP-1 COMPLEXED WITH CHOLINE==
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<StructureSection load='1oba' size='340' side='right' caption='[[1oba]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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==Multimodular Pneumococcal Cell Wall Endolysin from phage Cp-1 complexed with choline==
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<StructureSection load='1oba' size='340' side='right'caption='[[1oba]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1oba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_phage_cp-1 Streptococcus phage cp-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OBA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1oba]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_phage_Cp1 Streptococcus phage Cp1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OBA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHT:CHOLINE+ION'>CHT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h09|1h09]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHT:CHOLINE+ION'>CHT</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oba OCA], [https://pdbe.org/1oba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oba RCSB], [https://www.ebi.ac.uk/pdbsum/1oba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oba ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oba OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oba RCSB], [http://www.ebi.ac.uk/pdbsum/1oba PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYS_BPCP1 LYS_BPCP1] Responsible for the separation of the host daughter cells at the end of cell division and participates in the liberation of progeny bacteriophage into the medium. Strictly depends on the presence of choline-containing cell walls for activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1oba_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1oba_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oba ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1oba" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Lysin 3D structures|Lysin 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Streptococcus phage cp-1]]
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[[Category: Streptococcus phage Cp1]]
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[[Category: Albert, A]]
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[[Category: Albert A]]
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[[Category: Garcia, J L]]
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[[Category: Garcia JL]]
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[[Category: Garcia, P]]
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[[Category: Garcia P]]
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[[Category: Hermoso, J A]]
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[[Category: Hermoso JA]]
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[[Category: Martinez-Ripoll, M]]
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[[Category: Martinez-Ripoll M]]
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[[Category: Menendez, M]]
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[[Category: Menendez M]]
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[[Category: Monterroso, B]]
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[[Category: Monterroso B]]
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[[Category: Bacterilytic enzyme]]
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[[Category: Choline]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase glycosidase]]
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[[Category: Multimodular]]
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[[Category: Murein hydrolase]]
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[[Category: Phage cp- 1 lysin]]
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[[Category: Pneumococcal cell wall degradation]]
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Current revision

Multimodular Pneumococcal Cell Wall Endolysin from phage Cp-1 complexed with choline

PDB ID 1oba

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