1sfl

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==1.9A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, apo form==
==1.9A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, apo form==
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<StructureSection load='1sfl' size='340' side='right' caption='[[1sfl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='1sfl' size='340' side='right'caption='[[1sfl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1sfl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mrsa252 Staphylococcus aureus subsp. aureus mrsa252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SFL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1sfl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SFL FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sfj|1sfj]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=282458 Staphylococcus aureus subsp. aureus MRSA252])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfl OCA], [https://pdbe.org/1sfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sfl RCSB], [https://www.ebi.ac.uk/pdbsum/1sfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sfl ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sfl RCSB], [http://www.ebi.ac.uk/pdbsum/1sfl PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AROD_STAAR AROD_STAAR]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sfl_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sfl_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sfl ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Dehydroquinase|Dehydroquinase]]
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*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-dehydroquinate dehydratase]]
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus mrsa252]]
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[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
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[[Category: Hawkins, A R]]
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[[Category: Hawkins AR]]
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[[Category: Lockyer, M]]
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[[Category: Lockyer M]]
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[[Category: Nichols, C E]]
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[[Category: Nichols CE]]
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[[Category: Stammers, D K]]
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[[Category: Stammers DK]]
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[[Category: 3-dehydroquinase]]
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[[Category: 3-dehydroquinate]]
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[[Category: Enzyme turnover]]
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[[Category: Lyase]]
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[[Category: Shikimate pathway]]
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Current revision

1.9A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, apo form

PDB ID 1sfl

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