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1ol0

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==CRYSTAL STRUCTURE OF A CAMELISED HUMAN VH==
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<StructureSection load='1ol0' size='340' side='right' caption='[[1ol0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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==Crystal structure of a camelised human VH==
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<StructureSection load='1ol0' size='340' side='right'caption='[[1ol0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ol0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OL0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OL0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ol0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OL0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a8j|1a8j]], [[1aj7|1aj7]], [[1ar2|1ar2]], [[1b6d|1b6d]], [[1bm3|1bm3]], [[1bre|1bre]], [[1bww|1bww]], [[1cmo|1cmo]], [[1ek3|1ek3]], [[1epf|1epf]], [[1fig|1fig]], [[1ie5|1ie5]], [[1igm|1igm]], [[1ikf|1ikf]], [[1ind|1ind]], [[1ine|1ine]], [[1ivl|1ivl]], [[1jgl|1jgl]], [[1jvk|1jvk]], [[1koa|1koa]], [[1ksr|1ksr]], [[1lve|1lve]], [[1mcb|1mcb]], [[1mcc|1mcc]], [[1mcd|1mcd]], [[1mce|1mce]], [[1mcf|1mcf]], [[1mch|1mch]], [[1mci|1mci]], [[1mcj|1mcj]], [[1mck|1mck]], [[1mcl|1mcl]], [[1mcn|1mcn]], [[1mco|1mco]], [[1mcp|1mcp]], [[1mcq|1mcq]], [[1mcr|1mcr]], [[1mcs|1mcs]], [[1mcw|1mcw]], [[1rei|1rei]], [[1vkx|1vkx]], [[1wit|1wit]], [[1wiu|1wiu]], [[2dl2|2dl2]], [[2dli|2dli]], [[2fb4|2fb4]], [[2ig2|2ig2]], [[2imm|2imm]], [[2imn|2imn]], [[2loi|2loi]], [[2mcg|2mcg]], [[2mcp|2mcp]], [[2rcs|2rcs]], [[3mcg|3mcg]], [[5lve|5lve]], [[7fab|7fab]], [[8fab|8fab]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ol0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ol0 OCA], [https://pdbe.org/1ol0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ol0 RCSB], [https://www.ebi.ac.uk/pdbsum/1ol0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ol0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ol0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ol0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ol0 RCSB], [http://www.ebi.ac.uk/pdbsum/1ol0 PDBsum]</span></td></tr>
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</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ol/1ol0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ol/1ol0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ol0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1ol0" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dottorini, T]]
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[[Category: Large Structures]]
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[[Category: Losurdo, P]]
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[[Category: Dottorini T]]
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[[Category: Sollazzo, M]]
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[[Category: Losurdo P]]
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[[Category: Vaughan, C K]]
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[[Category: Sollazzo M]]
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[[Category: Walsh, M A]]
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[[Category: Vaughan CK]]
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[[Category: Camelised variable heavy domain]]
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[[Category: Walsh MA]]
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[[Category: Immunoglobulin]]
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Current revision

Crystal structure of a camelised human VH

PDB ID 1ol0

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