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1qbz

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==THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A==
==THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A==
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<StructureSection load='1qbz' size='340' side='right' caption='[[1qbz]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
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<StructureSection load='1qbz' size='340' side='right'caption='[[1qbz]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1qbz]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Simian_immunodeficiency_virus Simian immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QBZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1qbz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Simian_immunodeficiency_virus Simian immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QBZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qbz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qbz RCSB], [http://www.ebi.ac.uk/pdbsum/1qbz PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qbz OCA], [https://pdbe.org/1qbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qbz RCSB], [https://www.ebi.ac.uk/pdbsum/1qbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qbz ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/E7CWP5_SIV E7CWP5_SIV]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qb/1qbz_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qb/1qbz_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qbz ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1qbz" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Gp41|Gp41]]
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*[[Gp41 3D Structures|Gp41 3D Structures]]
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Simian immunodeficiency virus]]
[[Category: Simian immunodeficiency virus]]
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[[Category: Hyde, C C]]
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[[Category: Hyde CC]]
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[[Category: Kaufman, J]]
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[[Category: Kaufman J]]
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[[Category: Mueser, T C]]
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[[Category: Mueser TC]]
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[[Category: Stahl, S J]]
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[[Category: Stahl SJ]]
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[[Category: Wingfield, P T]]
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[[Category: Wingfield PT]]
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[[Category: Yang, Z N]]
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[[Category: Yang Z-N]]
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[[Category: Envelope glycoprotein]]
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[[Category: Gp41]]
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[[Category: Hiv]]
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[[Category: Membrane fusion]]
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[[Category: Peptide inhibitor]]
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[[Category: Siv]]
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[[Category: Siv envelope glycoprotein gp41]]
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Current revision

THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A

PDB ID 1qbz

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