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1rhh

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==Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution==
==Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution==
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<StructureSection load='1rhh' size='340' side='right' caption='[[1rhh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='1rhh' size='340' side='right'caption='[[1rhh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1rhh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RHH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1rhh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RHH FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g9n|1g9n]], [[1g9m|1g9m]], [[1hzh|1hzh]], [[3fct|3fct]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rhh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rhh RCSB], [http://www.ebi.ac.uk/pdbsum/1rhh PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rhh OCA], [https://pdbe.org/1rhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rhh RCSB], [https://www.ebi.ac.uk/pdbsum/1rhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rhh ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/1rhh_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/1rhh_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rhh ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1rhh" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Andrykovitch, M]]
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[[Category: Large Structures]]
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[[Category: Burton, D R]]
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[[Category: Andrykovitch M]]
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[[Category: Darbha, R]]
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[[Category: Burton DR]]
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[[Category: Dimitrov, D S]]
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[[Category: Darbha R]]
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[[Category: Gu, Y]]
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[[Category: Dimitrov DS]]
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[[Category: Ji, X]]
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[[Category: Gu Y]]
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[[Category: Labrijn, A F]]
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[[Category: Ji X]]
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[[Category: Martin, L]]
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[[Category: Labrijn AF]]
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[[Category: Pantophlet, R]]
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[[Category: Martin L]]
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[[Category: Phogat, S]]
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[[Category: Pantophlet R]]
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[[Category: Shu, Y]]
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[[Category: Phogat S]]
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[[Category: Vita, C]]
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[[Category: Shu Y]]
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[[Category: Zhang, M Y]]
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[[Category: Vita C]]
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[[Category: Antibody]]
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[[Category: Zhang MY]]
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[[Category: Broadly neutralizing]]
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[[Category: Fab]]
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[[Category: Hiv-1]]
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[[Category: Immune system]]
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[[Category: X5]]
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Current revision

Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution

PDB ID 1rhh

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