1w9v
From Proteopedia
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==Specificity and affinity of natural product cyclopentapeptide argifin against Aspergillus fumigatus== | ==Specificity and affinity of natural product cyclopentapeptide argifin against Aspergillus fumigatus== | ||
| - | <StructureSection load='1w9v' size='340' side='right' caption='[[1w9v]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='1w9v' size='340' side='right'caption='[[1w9v]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1w9v]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1w9v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus Aspergillus fumigatus] and [https://en.wikipedia.org/wiki/Gliocladium Gliocladium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W9V FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=MEA:N-METHYLPHENYLALANINE'>MEA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VR0:N~5~-[N-(METHYLCARBAMOYL)CARBAMIMIDOYL]-L-ORNITHINE'>VR0</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9v OCA], [https://pdbe.org/1w9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w9v RCSB], [https://www.ebi.ac.uk/pdbsum/1w9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w9v ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CHIB1_ASPFU CHIB1_ASPFU] Major secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Plays a role in the morphogenesis and autolysis (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/1w9v_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/1w9v_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w9v ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1w9v" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Chitinase|Chitinase]] | + | *[[Chitinase 3D structures|Chitinase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aspergillus fumigatus]] | [[Category: Aspergillus fumigatus]] | ||
| - | [[Category: | + | [[Category: Gliocladium]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Adams | + | [[Category: Adams DJ]] |
| - | [[Category: Aerts | + | [[Category: Aerts JMFG]] |
| - | [[Category: Boot | + | [[Category: Boot RG]] |
| - | [[Category: Hodkinson | + | [[Category: Hodkinson M]] |
| - | [[Category: Houston | + | [[Category: Houston DR]] |
| - | [[Category: Omura | + | [[Category: Omura S]] |
| - | [[Category: Rao | + | [[Category: Rao FV]] |
| - | [[Category: Shiomi | + | [[Category: Shiomi K]] |
| - | [[Category: | + | [[Category: Van Aalten DMF]] |
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Current revision
Specificity and affinity of natural product cyclopentapeptide argifin against Aspergillus fumigatus
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Categories: Aspergillus fumigatus | Gliocladium | Large Structures | Adams DJ | Aerts JMFG | Boot RG | Hodkinson M | Houston DR | Omura S | Rao FV | Shiomi K | Van Aalten DMF
