1vyv

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==BETA4 SUBUNIT OF CA2+ CHANNEL==
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<StructureSection load='1vyv' size='340' side='right' caption='[[1vyv]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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==beta4 subunit of Ca2+ channel==
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<StructureSection load='1vyv' size='340' side='right'caption='[[1vyv]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1vyv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VYV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VYV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1vyv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VYV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VYV FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vyt|1vyt]], [[1vyu|1vyu]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vyv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vyv RCSB], [http://www.ebi.ac.uk/pdbsum/1vyv PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vyv OCA], [https://pdbe.org/1vyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vyv RCSB], [https://www.ebi.ac.uk/pdbsum/1vyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vyv ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CACB4_RAT CACB4_RAT] The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.[UniProtKB:O00305]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vy/1vyv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vy/1vyv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vyv ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1vyv" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Ion channels|Ion channels]]
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*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Chen, Y H]]
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[[Category: Chen Y-H]]
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[[Category: Fitzmaurice, A]]
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[[Category: Fitzmaurice A]]
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[[Category: He, L L]]
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[[Category: He L-L]]
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[[Category: Li, M H]]
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[[Category: Li M-H]]
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[[Category: Liang, T]]
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[[Category: Liang T]]
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[[Category: Yamada, Y]]
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[[Category: Yamada Y]]
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[[Category: Yang, J]]
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[[Category: Yang J]]
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[[Category: Yang, S]]
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[[Category: Yang S]]
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[[Category: Zhang, H]]
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[[Category: Zhang H]]
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[[Category: Zhang, Y]]
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[[Category: Zhang Y]]
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[[Category: Aid doamin]]
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[[Category: Calcium channel beta subunit]]
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[[Category: Ion transport]]
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[[Category: Ion transport-complex]]
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[[Category: Ionic channel]]
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[[Category: Sh3 domain]]
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[[Category: Transport protein]]
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[[Category: Voltage-gated channel]]
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Current revision

beta4 subunit of Ca2+ channel

PDB ID 1vyv

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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