1u9s

<StructureSection load='1u9s' size='340' side='right' caption='[[1u9s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>

<table><tr><td colspan='2'>[[1u9s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U9S FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nbs|1nbs]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u9s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u9s RCSB], [http://www.ebi.ac.uk/pdbsum/1u9s PDBsum]</span></td></tr>

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== Publication Abstract from PubMed ==

Large RNA molecules, such as ribozymes, fold with well-defined tertiary structures that are important for their activity. There are many instances of ribozymes with identical function but differences in their secondary structures, suggesting alternative tertiary folds. Here, we report a crystal structure of the 161-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary structure from the specificity domain of a B-type molecule. Despite the differences, the cores of the domains have similar three-dimensional structure. Remarkably, the similar geometry of the cores is stabilized by a different set of interactions involving distinct auxiliary elements.

Basis for structural diversity in homologous RNAs.,Krasilnikov AS, Xiao Y, Pan T, Mondragon A Science. 2004 Oct 1;306(5693):104-7. PMID:15459389<ref>PMID:15459389</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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*[[Ribonuclease|Ribonuclease]]

[[Category: Krasilnikov, A S]]

[[Category: Specificity domain]]

[[Category: Trna]]