2iw2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (01:04, 21 November 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2iw2.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of human Prolidase==
-
|PDB= 2iw2 |SIZE=350|CAPTION= <scene name='initialview01'>2iw2</scene>, resolution 1.82&Aring;
+
<StructureSection load='2iw2' size='340' side='right'caption='[[2iw2]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
-
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+A'>AC1</scene>
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
+
<table><tr><td colspan='2'>[[2iw2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IW2 FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/Xaa-Pro_dipeptidase Xaa-Pro dipeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.13.9 3.4.13.9]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iw2 OCA], [https://pdbe.org/2iw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iw2 RCSB], [https://www.ebi.ac.uk/pdbsum/2iw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iw2 ProSAT]</span></td></tr>
-
 
+
</table>
-
'''CRYSTAL STRUCTURE OF HUMAN PROLIDASE'''
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
 
+
Check<jmol>
-
==Disease==
+
<jmolCheckbox>
-
Known disease associated with this structure: Prolidase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=170100 170100]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iw2_consurf.spt"</scriptWhenChecked>
-
 
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
-
==About this Structure==
+
<text>to colour the structure by Evolutionary Conservation</text>
-
2IW2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IW2 OCA].
+
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iw2 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Xaa-Pro dipeptidase]]
+
[[Category: Behlke J]]
-
[[Category: Behlke, J.]]
+
[[Category: Buessow K]]
-
[[Category: Buessow, K.]]
+
[[Category: Goetz F]]
-
[[Category: Goetz, F.]]
+
[[Category: Heinemann U]]
-
[[Category: Heinemann, U.]]
+
[[Category: Mueller U]]
-
[[Category: Mueller, U.]]
+
[[Category: Niesen FH]]
-
[[Category: Niesen, F H.]]
+
[[Category: Roske Y]]
-
[[Category: Roske, Y.]]
+
-
[[Category: NA]]
+
-
[[Category: acetylation]]
+
-
[[Category: collagen degradation]]
+
-
[[Category: dipeptidase]]
+
-
[[Category: disease mutation]]
+
-
[[Category: enzyme]]
+
-
[[Category: hydrolase]]
+
-
[[Category: manganese]]
+
-
[[Category: metal-binding]]
+
-
[[Category: metalloaminopeptidase]]
+
-
[[Category: metallocarboxypeptidase]]
+
-
[[Category: metalloprotease]]
+
-
[[Category: pepd gene]]
+
-
[[Category: peptidase d]]
+
-
[[Category: phosphorylation]]
+
-
[[Category: polymorphism]]
+
-
[[Category: protease]]
+
-
[[Category: xaa-pro dipeptidase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:34:03 2008''
+

Current revision

Crystal structure of human Prolidase

PDB ID 2iw2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2iw2"
Personal tools