2bsd

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==STRUCTURE OF LACTOCOCCAL BACTERIOPHAGE P2 RECEPTOR BINDING PROTEIN==
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<StructureSection load='2bsd' size='340' side='right' caption='[[2bsd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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==Structure of Lactococcal Bacteriophage p2 Receptor Binding Protein==
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<StructureSection load='2bsd' size='340' side='right'caption='[[2bsd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bsd]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p2 Enterobacteria phage p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BSD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bsd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_P2 Escherichia virus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BSD FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bse|2bse]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bsd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bsd RCSB], [http://www.ebi.ac.uk/pdbsum/2bsd PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bsd OCA], [https://pdbe.org/2bsd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bsd RCSB], [https://www.ebi.ac.uk/pdbsum/2bsd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bsd ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RBP_BPLP2 RBP_BPLP2] Binds to the host phosphopolysaccharides at the onset of infection. Upon activation by calcium, the receptor binding proteins change their conformation, presenting their binding sites to the host, and a channel opens at the bottom of the baseplate for DNA ejection.<ref>PMID:20351260</ref> <ref>PMID:24027307</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/2bsd_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/2bsd_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bsd ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2bsd" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enterobacteria phage p2]]
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[[Category: Escherichia virus P2]]
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[[Category: Cambillau, C]]
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[[Category: Large Structures]]
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[[Category: Dehaard, H J.W]]
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[[Category: Cambillau C]]
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[[Category: Desmyter, A]]
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[[Category: Dehaard HJW]]
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[[Category: Moineau, S]]
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[[Category: Desmyter A]]
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[[Category: Spinelli, S]]
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[[Category: Moineau S]]
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[[Category: Verrips, C T]]
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[[Category: Spinelli S]]
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[[Category: Lactococcus lacti]]
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[[Category: Verrips CT]]
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[[Category: Llama vhh]]
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[[Category: Phage]]
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[[Category: Receptor]]
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[[Category: Receptor binding protein]]
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Current revision

Structure of Lactococcal Bacteriophage p2 Receptor Binding Protein

PDB ID 2bsd

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