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2afp

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==THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY==
==THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY==
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<StructureSection load='2afp' size='340' side='right' caption='[[2afp]], [[NMR_Ensembles_of_Models | 5 NMR models]]' scene=''>
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<StructureSection load='2afp' size='340' side='right'caption='[[2afp]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2afp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hemitripterus_americanus Hemitripterus americanus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AFP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2afp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hemitripterus_americanus Hemitripterus americanus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AFP FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2afp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2afp RCSB], [http://www.ebi.ac.uk/pdbsum/2afp PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2afp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afp OCA], [https://pdbe.org/2afp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2afp RCSB], [https://www.ebi.ac.uk/pdbsum/2afp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2afp ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ISP2_HEMAM ISP2_HEMAM] Antifreeze proteins lower the blood freezing point.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/af/2afp_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/af/2afp_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2afp ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2afp" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Antifreeze protein|Antifreeze protein]]
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*[[Antifreeze protein 3D structures|Antifreeze protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Hemitripterus americanus]]
[[Category: Hemitripterus americanus]]
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[[Category: Daugulis, A J]]
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[[Category: Large Structures]]
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[[Category: Davies, P L]]
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[[Category: Daugulis AJ]]
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[[Category: Gronwald, W]]
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[[Category: Davies PL]]
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[[Category: Lix, B]]
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[[Category: Gronwald W]]
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[[Category: Loewen, M C]]
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[[Category: Lix B]]
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[[Category: Sonnichsen, F D]]
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[[Category: Loewen MC]]
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[[Category: Sykes, B D]]
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[[Category: Sonnichsen FD]]
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[[Category: Antifreeze protein]]
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[[Category: Sykes BD]]
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[[Category: C-type lectin]]
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[[Category: Recombinant sea raven protein]]
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[[Category: Solution backbone fold]]
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Current revision

THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY

PDB ID 2afp

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