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1zru
From Proteopedia
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==structure of the lactophage p2 receptor binding protein in complex with glycerol== | ==structure of the lactophage p2 receptor binding protein in complex with glycerol== | ||
| - | <StructureSection load='1zru' size='340' side='right' caption='[[1zru]], [[Resolution|resolution]] 1.73Å' scene=''> | + | <StructureSection load='1zru' size='340' side='right'caption='[[1zru]], [[Resolution|resolution]] 1.73Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1zru]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1zru]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_virus_P2 Lactococcus virus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZRU FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zru OCA], [https://pdbe.org/1zru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zru RCSB], [https://www.ebi.ac.uk/pdbsum/1zru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zru ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RBP_BPLP2 RBP_BPLP2] Binds to the host phosphopolysaccharides at the onset of infection. Upon activation by calcium, the receptor binding proteins change their conformation, presenting their binding sites to the host, and a channel opens at the bottom of the baseplate for DNA ejection.<ref>PMID:20351260</ref> <ref>PMID:24027307</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zru_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zru_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zru ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1zru" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Lactococcus | + | [[Category: Lactococcus virus P2]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Blangy S]] |
| - | [[Category: | + | [[Category: Cambillau C]] |
| - | [[Category: | + | [[Category: Desmyter A]] |
| - | [[Category: Huyghe | + | [[Category: Huyghe C]] |
| - | [[Category: Labrie | + | [[Category: Labrie S]] |
| - | [[Category: Moineau | + | [[Category: Moineau S]] |
| - | + | [[Category: Spinelli S]] | |
| - | [[Category: Spinelli | + | [[Category: Tegoni M]] |
| - | [[Category: Tegoni | + | [[Category: Tremblay DM]] |
| - | [[Category: Tremblay | + | [[Category: De Haard H]] |
| - | [[Category: | + | |
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Current revision
structure of the lactophage p2 receptor binding protein in complex with glycerol
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Categories: Lactococcus virus P2 | Large Structures | Blangy S | Cambillau C | Desmyter A | Huyghe C | Labrie S | Moineau S | Spinelli S | Tegoni M | Tremblay DM | De Haard H
