1z6k

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==Citrate lyase beta subunit complexed with oxaloacetate and magnesium from M. tuberculosis==
==Citrate lyase beta subunit complexed with oxaloacetate and magnesium from M. tuberculosis==
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<StructureSection load='1z6k' size='340' side='right' caption='[[1z6k]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='1z6k' size='340' side='right'caption='[[1z6k]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1z6k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z6K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1z6k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z6K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u5h|1u5h]], [[1sgj|1sgj]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6k OCA], [https://pdbe.org/1z6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z6k RCSB], [https://www.ebi.ac.uk/pdbsum/1z6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z6k ProSAT], [https://www.topsan.org/Proteins/TBSGC/1z6k TOPSAN]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv2498c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Citrate_(pro-3S)-lyase Citrate (pro-3S)-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.6 4.1.3.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z6k RCSB], [http://www.ebi.ac.uk/pdbsum/1z6k PDBsum], [http://www.topsan.org/Proteins/TBSGC/1z6k TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CITEL_MYCTU CITEL_MYCTU] May play a role in fatty acid biosynthesis (Potential).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/1z6k_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/1z6k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z6k ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1z6k" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Large Structures]]
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[[Category: Bowers, P M]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Eisenberg, D]]
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[[Category: Bowers PM]]
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[[Category: Goulding, C W]]
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[[Category: Eisenberg D]]
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[[Category: Kim, C Y]]
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[[Category: Goulding CW]]
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[[Category: Lekin, T]]
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[[Category: Kim CY]]
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[[Category: Segelke, B]]
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[[Category: Lekin T]]
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[[Category: Structural genomic]]
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[[Category: Segelke B]]
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[[Category: Terwilliger, T C]]
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[[Category: Terwilliger TC]]
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[[Category: Lyase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Tbsgc]]
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[[Category: Tim barrel]]
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Current revision

Citrate lyase beta subunit complexed with oxaloacetate and magnesium from M. tuberculosis

PDB ID 1z6k

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