2dk6
From Proteopedia
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==Solution structure of WWE domain in poly (ADP-ribose) polymerase family, member 11 (PARP 11)== | ==Solution structure of WWE domain in poly (ADP-ribose) polymerase family, member 11 (PARP 11)== | ||
| - | <StructureSection load='2dk6' size='340' side='right' caption='[[2dk6 | + | <StructureSection load='2dk6' size='340' side='right'caption='[[2dk6]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dk6]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dk6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DK6 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk6 OCA], [https://pdbe.org/2dk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dk6 RCSB], [https://www.ebi.ac.uk/pdbsum/2dk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk6 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dk6 TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAR11_HUMAN PAR11_HUMAN] Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins (PubMed:25043379, PubMed:25673562). Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (By similarity).[UniProtKB:Q8CFF0]<ref>PMID:25043379</ref> <ref>PMID:25673562</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dk6_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dk6_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dk6 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]] | + | *[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: He | + | [[Category: Large Structures]] |
| - | [[Category: Inoue | + | [[Category: He F]] |
| - | [[Category: Kigawa | + | [[Category: Inoue M]] |
| - | [[Category: Muto | + | [[Category: Kigawa T]] |
| - | + | [[Category: Muto Y]] | |
| - | [[Category: Shirouzu | + | [[Category: Shirouzu M]] |
| - | [[Category: Terada | + | [[Category: Terada T]] |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
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Current revision
Solution structure of WWE domain in poly (ADP-ribose) polymerase family, member 11 (PARP 11)
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Categories: Homo sapiens | Large Structures | He F | Inoue M | Kigawa T | Muto Y | Shirouzu M | Terada T | Yokoyama S
