2fh8

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==Crystal Structure Analysis of Klebsiella pneumoniae pullulanase complexed with isomaltose==
==Crystal Structure Analysis of Klebsiella pneumoniae pullulanase complexed with isomaltose==
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<StructureSection load='2fh8' size='340' side='right' caption='[[2fh8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='2fh8' size='340' side='right'caption='[[2fh8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fh8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacter_aerogenes Enterobacter aerogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FH8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FH8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fh8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FH8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fgz|2fgz]], [[2fh6|2fh6]], [[2fhb|2fhb]], [[2fhc|2fhc]], [[2fhf|2fhf]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pullulanase Pullulanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.41 3.2.1.41] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fh8 OCA], [https://pdbe.org/2fh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fh8 RCSB], [https://www.ebi.ac.uk/pdbsum/2fh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fh8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fh8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fh8 RCSB], [http://www.ebi.ac.uk/pdbsum/2fh8 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/W9BQ28_KLEPN W9BQ28_KLEPN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fh/2fh8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fh/2fh8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fh8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2fh8" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Amylase|Amylase]]
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*[[Amylase 3D structures|Amylase 3D structures]]
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*[[User:Gabriel Pons/Sandbox 2|User:Gabriel Pons/Sandbox 2]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enterobacter aerogenes]]
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[[Category: Klebsiella pneumoniae]]
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[[Category: Pullulanase]]
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[[Category: Large Structures]]
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[[Category: Demirkan-Sarikaya, E]]
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[[Category: Demirkan-Sarikaya E]]
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[[Category: Iwamoto, H]]
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[[Category: Iwamoto H]]
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[[Category: Katsuya, Y]]
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[[Category: Katsuya Y]]
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[[Category: Malle, D]]
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[[Category: Malle D]]
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[[Category: Mikami, B]]
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[[Category: Mikami B]]
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[[Category: Yoon, H J]]
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[[Category: Yoon H-J]]
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[[Category: Alpha-amylase-family]]
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[[Category: Beta-alpha-barrel]]
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[[Category: Complex with isomaltose]]
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[[Category: Hydrolase]]
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[[Category: Multiple domain]]
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Current revision

Crystal Structure Analysis of Klebsiella pneumoniae pullulanase complexed with isomaltose

PDB ID 2fh8

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