2otg

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==Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor==
==Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor==
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<StructureSection load='2otg' size='340' side='right' caption='[[2otg]], [[Resolution|resolution]] 3.12&Aring;' scene=''>
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<StructureSection load='2otg' size='340' side='right'caption='[[2otg]], [[Resolution|resolution]] 3.12&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2otg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Placopecten_magellanicus Placopecten magellanicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OTG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OTG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2otg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Placopecten_magellanicus Placopecten magellanicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OTG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.12&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2os8|2os8]], [[1kk7|1kk7]], [[1kk8|1kk8]], [[1sr6|1sr6]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2otg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2otg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2otg RCSB], [http://www.ebi.ac.uk/pdbsum/2otg PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2otg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2otg OCA], [https://pdbe.org/2otg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2otg RCSB], [https://www.ebi.ac.uk/pdbsum/2otg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2otg ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q26080_PLAMG Q26080_PLAMG]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/2otg_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/2otg_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2otg ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2otg" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Myosin|Myosin]]
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*[[Myosin 3D Structures|Myosin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Placopecten magellanicus]]
[[Category: Placopecten magellanicus]]
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[[Category: Brown, J H]]
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[[Category: Brown JH]]
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[[Category: Cohen, C]]
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[[Category: Cohen C]]
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[[Category: Gourinath, S]]
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[[Category: Gourinath S]]
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[[Category: Himmel, D M]]
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[[Category: Himmel DM]]
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[[Category: Kovacs, M]]
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[[Category: Kovacs M]]
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[[Category: Neall-Hennessey, E O]]
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[[Category: Nyitray L]]
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[[Category: Nyitray, L]]
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[[Category: O'Neall-Hennessey E]]
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[[Category: Reshetnikova, L]]
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[[Category: Reshetnikova L]]
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[[Category: Reutzel, R]]
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[[Category: Reutzel R]]
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[[Category: Szent-Gyorgyi, A G]]
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[[Category: Szent-Gyorgyi AG]]
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[[Category: Yang, Y]]
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[[Category: Yang Y]]
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[[Category: Contractile protein]]
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[[Category: Motor]]
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[[Category: Myosin s1]]
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[[Category: Rigor-like]]
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Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor

PDB ID 2otg

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