2wao

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:10, 9 May 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
==STRUCTURE OF A FAMILY TWO CARBOHYDRATE ESTERASE FROM CLOSTRIDIUM THERMOCELLUM IN COMPLEX WITH CELLOHEXAOSE==
+
 
-
<StructureSection load='2wao' size='340' side='right' caption='[[2wao]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+
==Structure of a family two carbohydrate esterase from Clostridium thermocellum in complex with cellohexaose==
 +
<StructureSection load='2wao' size='340' side='right'caption='[[2wao]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2wao]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WAO FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2wao]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WAO FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wab|2wab]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PRD_900016:beta-cellopentaose'>PRD_900016</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wao OCA], [https://pdbe.org/2wao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wao RCSB], [https://www.ebi.ac.uk/pdbsum/2wao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wao ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wao OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wao RCSB], [http://www.ebi.ac.uk/pdbsum/2wao PDBsum]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CELE_ACET2 CELE_ACET2] Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan (PubMed:3066698, PubMed:1991028). Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) (PubMed:19338387).<ref>PMID:19338387</ref> <ref>PMID:1991028</ref> <ref>PMID:3066698</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wao_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wao_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wao ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 26: Line 28:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2wao" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Glucanase|Glucanase]]
+
*[[Glucanase 3D structures|Glucanase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Cellulase]]
+
[[Category: Acetivibrio thermocellus]]
-
[[Category: Clostridium thermocellum]]
+
[[Category: Large Structures]]
-
[[Category: Bolam, D N]]
+
[[Category: Bolam DN]]
-
[[Category: Davies, G J]]
+
[[Category: Davies GJ]]
-
[[Category: Dodson, E J]]
+
[[Category: Dodson EJ]]
-
[[Category: Flint, J E]]
+
[[Category: Flint JE]]
-
[[Category: Fontes, C M.G A]]
+
[[Category: Fontes CMGA]]
-
[[Category: Gilbert, H J]]
+
[[Category: Gilbert HJ]]
-
[[Category: Goyal, A]]
+
[[Category: Goyal A]]
-
[[Category: Izumi, A]]
+
[[Category: Izumi A]]
-
[[Category: Kolenova, K]]
+
[[Category: Kolenova K]]
-
[[Category: Money, V A]]
+
[[Category: Money VA]]
-
[[Category: Montainer, C]]
+
[[Category: Montainer C]]
-
[[Category: Pinheiro, B A]]
+
[[Category: Pinheiro BA]]
-
[[Category: Pires, V M.R]]
+
[[Category: Pires VMR]]
-
[[Category: Prates, J A.M]]
+
[[Category: Prates JAM]]
-
[[Category: Stalbrand, H]]
+
[[Category: Stalbrand H]]
-
[[Category: Topakas, E]]
+
[[Category: Topakas E]]
-
[[Category: Carbohydrate binding]]
+
-
[[Category: Carbohydrate metabolism]]
+
-
[[Category: Cellulose degradation]]
+
-
[[Category: Esterase]]
+
-
[[Category: Glycosidase]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Plant cell wall degradation]]
+
-
[[Category: Polysaccharide degradation]]
+

Current revision

Structure of a family two carbohydrate esterase from Clostridium thermocellum in complex with cellohexaose

PDB ID 2wao

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools