2nxu

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[[Image:2nxu.gif|left|200px]]
 
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{{Structure
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==Atomic structure of translation initiation factor aIF2 beta-subunit from Archaebacteria sulfolobus solfataricus: high resolution NMR in solution==
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|PDB= 2nxu |SIZE=350|CAPTION= <scene name='initialview01'>2nxu</scene>
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<StructureSection load='2nxu' size='340' side='right'caption='[[2nxu]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2nxu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NXU FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= eif2b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nxu OCA], [https://pdbe.org/2nxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nxu RCSB], [https://www.ebi.ac.uk/pdbsum/2nxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nxu ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Atomic structure of translation initiation factor aIF2 beta-subunit from Archaebacteria sulfolobus solfataricus: high resolution NMR in solution'''
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[https://www.uniprot.org/uniprot/IF2B_SACS2 IF2B_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00232]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2NXU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXU OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/2nxu_consurf.spt"</scriptWhenChecked>
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==Reference==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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Solution structure of the beta-subunit of the translation initiation factor aIF2 from archaebacteria Sulfolobus solfataricus., Vasile F, Pechkova E, Nicolini C, Proteins. 2008 Feb 15;70(3):1112-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18004773 18004773]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: Sulfolobus solfataricus]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nxu ConSurf].
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[[Category: Garber, M.]]
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<div style="clear:both"></div>
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[[Category: Nicolini, C.]]
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__TOC__
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[[Category: Pechkova, E.]]
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</StructureSection>
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[[Category: Stolboushkina, E.]]
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[[Category: Large Structures]]
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[[Category: Vasile, F.]]
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[[Category: Saccharolobus solfataricus P2]]
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[[Category: aif2beta]]
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[[Category: Garber M]]
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[[Category: archaea]]
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[[Category: Nicolini C]]
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[[Category: nmr structure]]
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[[Category: Pechkova E]]
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[[Category: translation initiation factor]]
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[[Category: Stolboushkina E]]
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[[Category: Vasile F]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:52:34 2008''
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Current revision

Atomic structure of translation initiation factor aIF2 beta-subunit from Archaebacteria sulfolobus solfataricus: high resolution NMR in solution

PDB ID 2nxu

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