2va1

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==CRYSTAL STRUCTURE OF UMP KINASE FROM UREAPLASMA PARVUM==
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<StructureSection load='2va1' size='340' side='right' caption='[[2va1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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==Crystal structure of UMP kinase from Ureaplasma parvum==
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<StructureSection load='2va1' size='340' side='right'caption='[[2va1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2va1]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Ureaplasma_parvum Ureaplasma parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VA1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2va1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Ureaplasma_parvum Ureaplasma parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VA1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2va1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2va1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2va1 RCSB], [http://www.ebi.ac.uk/pdbsum/2va1 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2va1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2va1 OCA], [https://pdbe.org/2va1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2va1 RCSB], [https://www.ebi.ac.uk/pdbsum/2va1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2va1 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRH_UREPA PYRH_UREPA] Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor. Is also able to phosphorylate dUMP.<ref>PMID:17355283</ref> <ref>PMID:18021254</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2va1_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2va1_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2va1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2va1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Ureaplasma parvum]]
[[Category: Ureaplasma parvum]]
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[[Category: Egeblad-Welin, L]]
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[[Category: Egeblad-Welin L]]
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[[Category: Eriksson, S]]
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[[Category: Eriksson S]]
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[[Category: Wang, L]]
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[[Category: Wang L]]
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[[Category: Welin, M]]
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[[Category: Welin M]]
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[[Category: Amino acid kinase family]]
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[[Category: Kinase]]
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[[Category: Pyrimidine biosynthesis]]
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[[Category: Transferase]]
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[[Category: Umpk]]
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[[Category: Uridylate kinase]]
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Current revision

Crystal structure of UMP kinase from Ureaplasma parvum

PDB ID 2va1

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