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2ivz

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==STRUCTURE OF TOLB IN COMPLEX WITH A PEPTIDE OF THE COLICIN E9 T-DOMAIN==
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<StructureSection load='2ivz' size='340' side='right' caption='[[2ivz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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==Structure of TolB in complex with a peptide of the colicin E9 T- domain==
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<StructureSection load='2ivz' size='340' side='right'caption='[[2ivz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ivz]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ivz]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IVZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bxi|1bxi]], [[1c5k|1c5k]], [[1crz|1crz]], [[1emv|1emv]], [[1fr2|1fr2]], [[1fsj|1fsj]], [[1v13|1v13]], [[1v14|1v14]], [[1v15|1v15]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ivz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ivz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ivz RCSB], [http://www.ebi.ac.uk/pdbsum/2ivz PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ivz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ivz OCA], [https://pdbe.org/2ivz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ivz RCSB], [https://www.ebi.ac.uk/pdbsum/2ivz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ivz ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TOLB_ECOLI TOLB_ECOLI] Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K). Necessary for the colicins to reach their respective targets after initial binding to the bacteria.[HAMAP-Rule:MF_00671]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iv/2ivz_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iv/2ivz_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ivz ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2ivz" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Colicin|Colicin]]
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*[[Colicin 3D structures|Colicin 3D structures]]
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*[[Tol|Tol]]
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*[[TolB|TolB]]
*[[TolB|TolB]]
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*[[TonB|TonB]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Bonsor, D A]]
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[[Category: Large Structures]]
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[[Category: James, R]]
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[[Category: Bonsor DA]]
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[[Category: Kleanthous, C]]
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[[Category: James R]]
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[[Category: Loftus, S R]]
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[[Category: Kleanthous C]]
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[[Category: Mate, M J]]
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[[Category: Loftus SR]]
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[[Category: Moore, G R]]
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[[Category: Mate MJ]]
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[[Category: Walker, D]]
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[[Category: Moore GR]]
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[[Category: Antibiotic]]
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[[Category: Walker D]]
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[[Category: Antimicrobial]]
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[[Category: Bacteriocin]]
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[[Category: Bacteriocin transport]]
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[[Category: Colicin]]
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[[Category: Endonuclease]]
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[[Category: Hydrolase]]
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[[Category: Natively disordered protein]]
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[[Category: Nuclease]]
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[[Category: Periplasmic]]
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[[Category: Protein transport]]
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[[Category: Protein transport-hydrolase complex]]
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[[Category: Protein transport/hydrolase]]
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[[Category: Protein-protein interaction]]
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[[Category: Tolb]]
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[[Category: Translocation]]
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[[Category: Transport]]
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Current revision

Structure of TolB in complex with a peptide of the colicin E9 T- domain

PDB ID 2ivz

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