2pfm

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==Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis==
==Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis==
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<StructureSection load='2pfm' size='340' side='right' caption='[[2pfm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2pfm' size='340' side='right'caption='[[2pfm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pfm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PFM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pfm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">purB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylosuccinate_lyase Adenylosuccinate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.2.2 4.3.2.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfm OCA], [https://pdbe.org/2pfm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pfm RCSB], [https://www.ebi.ac.uk/pdbsum/2pfm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pfm RCSB], [http://www.ebi.ac.uk/pdbsum/2pfm PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A6L8PR48_BACAN A0A6L8PR48_BACAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pf/2pfm_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pf/2pfm_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pfm ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenylosuccinate lyase]]
 
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Baumgart, M]]
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[[Category: Large Structures]]
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[[Category: Blagova, E V]]
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[[Category: Baumgart M]]
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[[Category: Levdikov, V M]]
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[[Category: Blagova EV]]
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[[Category: Moroz, O V]]
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[[Category: Levdikov VM]]
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[[Category: Wilkinson, A J]]
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[[Category: Moroz OV]]
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[[Category: Wilson, K S]]
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[[Category: Wilkinson AJ]]
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[[Category: Ba0290]]
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[[Category: Wilson KS]]
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[[Category: Lyase]]
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[[Category: Purb]]
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[[Category: Purine biosynthesis]]
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Current revision

Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis

PDB ID 2pfm

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