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2w9o

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==SOLUTION STRUCTURE OF JERDOSTATIN FROM TRIMERESURUS JERDONII==
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<StructureSection load='2w9o' size='340' side='right' caption='[[2w9o]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
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==Solution structure of jerdostatin from Trimeresurus jerdonii==
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<StructureSection load='2w9o' size='340' side='right'caption='[[2w9o]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w9o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Protobothrops_jerdonii Protobothrops jerdonii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w9o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Protobothrops_jerdonii Protobothrops jerdonii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9O FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w9u|2w9u]], [[2w9v|2w9v]], [[2w9w|2w9w]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9o OCA], [https://pdbe.org/2w9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9o RCSB], [https://www.ebi.ac.uk/pdbsum/2w9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9o ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9o RCSB], [http://www.ebi.ac.uk/pdbsum/2w9o PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DIS_PROJR DIS_PROJR] Recombinant protein inhibits the adhesion of alpha-1/beta-1-K562 (ITGA1/ITGB1) cells to collagen IV with an IC(50) of 80 nM.<ref>PMID:16215260</ref> <ref>PMID:21656569</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9o_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9o_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w9o ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2w9o" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Protobothrops jerdonii]]
[[Category: Protobothrops jerdonii]]
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[[Category: Calvete, J J]]
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[[Category: Calvete JJ]]
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[[Category: Carbajo, R J]]
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[[Category: Carbajo RJ]]
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[[Category: Mosulen, S]]
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[[Category: Mosulen S]]
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[[Category: Pineda-Lucena, A]]
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[[Category: Pineda-Lucena A]]
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[[Category: Sanz, L]]
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[[Category: Sanz L]]
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[[Category: Blood coagulation]]
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[[Category: Cell adhesion]]
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[[Category: Toxin]]
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[[Category: Venom]]
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Current revision

Solution structure of jerdostatin from Trimeresurus jerdonii

PDB ID 2w9o

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