2w9o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (01:28, 21 November 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
==SOLUTION STRUCTURE OF JERDOSTATIN FROM TRIMERESURUS JERDONII==
+
 
-
<StructureSection load='2w9o' size='340' side='right' caption='[[2w9o]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
+
==Solution structure of jerdostatin from Trimeresurus jerdonii==
 +
<StructureSection load='2w9o' size='340' side='right'caption='[[2w9o]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2w9o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Protobothrops_jerdonii Protobothrops jerdonii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9O FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2w9o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Protobothrops_jerdonii Protobothrops jerdonii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9O FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w9u|2w9u]], [[2w9v|2w9v]], [[2w9w|2w9w]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 40 models</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9o RCSB], [http://www.ebi.ac.uk/pdbsum/2w9o PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9o OCA], [https://pdbe.org/2w9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9o RCSB], [https://www.ebi.ac.uk/pdbsum/2w9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9o ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DIS_PROJR DIS_PROJR] Recombinant protein inhibits the adhesion of alpha-1/beta-1-K562 (ITGA1/ITGB1) cells to collagen IV with an IC(50) of 80 nM.<ref>PMID:16215260</ref> <ref>PMID:21656569</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9o_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9o_consurf.spt"</scriptWhenChecked>
-
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w9o ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 24: Line 27:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2w9o" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
Line 31: Line 35:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Protobothrops jerdonii]]
[[Category: Protobothrops jerdonii]]
-
[[Category: Calvete, J J]]
+
[[Category: Calvete JJ]]
-
[[Category: Carbajo, R J]]
+
[[Category: Carbajo RJ]]
-
[[Category: Mosulen, S]]
+
[[Category: Mosulen S]]
-
[[Category: Pineda-Lucena, A]]
+
[[Category: Pineda-Lucena A]]
-
[[Category: Sanz, L]]
+
[[Category: Sanz L]]
-
[[Category: Blood coagulation]]
+
-
[[Category: Cell adhesion]]
+
-
[[Category: Toxin]]
+
-
[[Category: Venom]]
+

Current revision

Solution structure of jerdostatin from Trimeresurus jerdonii

PDB ID 2w9o

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2w9o"
Personal tools