3ovn
From Proteopedia
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==Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase== | ==Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase== | ||
| - | <StructureSection load='3ovn' size='340' side='right' caption='[[3ovn]], [[Resolution|resolution]] 1.95Å' scene=''> | + | <StructureSection load='3ovn' size='340' side='right'caption='[[3ovn]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ovn]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ovn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OVN FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=MPV:1-METHYL-3-(THIOPHEN-2-YL)-1H-PYRAZOL-5-AMINE'>MPV</scene>, <scene name='pdbligand= | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MPV:1-METHYL-3-(THIOPHEN-2-YL)-1H-PYRAZOL-5-AMINE'>MPV</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ovn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ovn OCA], [https://pdbe.org/3ovn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ovn RCSB], [https://www.ebi.ac.uk/pdbsum/3ovn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ovn ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q72498_9HIV1 Q72498_9HIV1] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| - | [[Category: Chalmers | + | [[Category: Large Structures]] |
| - | [[Category: Deadman | + | [[Category: Chalmers DK]] |
| - | [[Category: Headey | + | [[Category: Deadman JJ]] |
| - | [[Category: Parker | + | [[Category: Headey SJ]] |
| - | [[Category: Rhodes | + | [[Category: Parker MW]] |
| - | [[Category: Scanlon | + | [[Category: Rhodes DK]] |
| - | [[Category: Wielens | + | [[Category: Scanlon MJ]] |
| - | + | [[Category: Wielens J]] | |
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Current revision
Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase
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