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2zx9

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==alpha-L-fucosidase complexed with inhibitor, B4==
==alpha-L-fucosidase complexed with inhibitor, B4==
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<StructureSection load='2zx9' size='340' side='right' caption='[[2zx9]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
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<StructureSection load='2zx9' size='340' side='right'caption='[[2zx9]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zx9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZX9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZX9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zx9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZX9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZX9:(2S)-2-CYCLOPENTYL-2-PHENYL-N-{[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYLPIPERIDIN-2-YL]METHYL}ETHANAMIDE'>ZX9</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hl8|1hl8]], [[2zwy|2zwy]], [[2zwz|2zwz]], [[2zx5|2zx5]], [[2zx6|2zx6]], [[2zx7|2zx7]], [[2zx8|2zx8]], [[2zxa|2zxa]], [[2zxb|2zxb]], [[2zxd|2zxd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZX9:(2S)-2-CYCLOPENTYL-2-PHENYL-N-{[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYLPIPERIDIN-2-YL]METHYL}ETHANAMIDE'>ZX9</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-L-fucosidase Alpha-L-fucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.51 3.2.1.51] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zx9 OCA], [https://pdbe.org/2zx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zx9 RCSB], [https://www.ebi.ac.uk/pdbsum/2zx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zx9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zx9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zx9 RCSB], [http://www.ebi.ac.uk/pdbsum/2zx9 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9WYE2_THEMA Q9WYE2_THEMA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zx9_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zx9_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zx9 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Alpha-L-fucosidase]]
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Ho, C W]]
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[[Category: Ho C-W]]
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[[Category: Ko, T P]]
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[[Category: Ko T-P]]
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[[Category: Lin, C H]]
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[[Category: Lin C-H]]
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[[Category: Wang, A H.J]]
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[[Category: Wang AH-J]]
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[[Category: Wu, H J]]
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[[Category: Wu H-J]]
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[[Category: Hydrolase]]
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[[Category: Tim barrel]]
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Current revision

alpha-L-fucosidase complexed with inhibitor, B4

PDB ID 2zx9

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