2z5g

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==Crystal structure of T1 lipase F16L mutant==
==Crystal structure of T1 lipase F16L mutant==
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<StructureSection load='2z5g' size='340' side='right' caption='[[2z5g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='2z5g' size='340' side='right'caption='[[2z5g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z5g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_zalihae Geobacillus zalihae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z5G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z5g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_zalihae Geobacillus zalihae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z5G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z5g RCSB], [http://www.ebi.ac.uk/pdbsum/2z5g PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z5g OCA], [https://pdbe.org/2z5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z5g RCSB], [https://www.ebi.ac.uk/pdbsum/2z5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z5g ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q842J9_9BACI Q842J9_9BACI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z5/2z5g_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z5/2z5g_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z5g ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Lipase|Lipase]]
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*[[Lipase 3D Structures|Lipase 3D Structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Geobacillus zalihae]]
[[Category: Geobacillus zalihae]]
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[[Category: Triacylglycerol lipase]]
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[[Category: Large Structures]]
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[[Category: Inoue, T]]
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[[Category: Inoue T]]
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[[Category: Kai, Y]]
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[[Category: Kai Y]]
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[[Category: Matsumura, H]]
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[[Category: Matsumura H]]
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[[Category: Yamamoto, T]]
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[[Category: Yamamoto T]]
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[[Category: Cation-pi interaction]]
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[[Category: Hydrolase]]
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[[Category: Lipase]]
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Current revision

Crystal structure of T1 lipase F16L mutant

PDB ID 2z5g

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