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4c70

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==Crystal structure of M. tuberculosis C171Q KasA in complex with TLM4==
==Crystal structure of M. tuberculosis C171Q KasA in complex with TLM4==
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<StructureSection load='4c70' size='340' side='right' caption='[[4c70]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4c70' size='340' side='right'caption='[[4c70]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4c70]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_sp._h37rv Mycobacterium sp. h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C70 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C70 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4c70]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C70 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=M7U:(2R)-2-(HEXADECANOYLOXY)-3-{[(10R)-10-METHYLOCTADECANOYL]OXY}PROPYL+PHOSPHATE'>M7U</scene>, <scene name='pdbligand=TLJ:(5R)-4-HYDROXY-5-METHYL-5-[(1E)-2-METHYLBUTA-1,3-DIEN-1-YL]-3-PROPYLTHIOPHEN-2(5H)-ONE'>TLJ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c6u|4c6u]], [[4c6v|4c6v]], [[4c6w|4c6w]], [[4c6x|4c6x]], [[4c6z|4c6z]], [[4c71|4c71]], [[4c72|4c72]], [[4c73|4c73]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=M7U:(2R)-2-(HEXADECANOYLOXY)-3-{[(10R)-10-METHYLOCTADECANOYL]OXY}PROPYL+PHOSPHATE'>M7U</scene>, <scene name='pdbligand=TLJ:(5R)-4-HYDROXY-5-METHYL-5-[(1E)-2-METHYLBUTA-1,3-DIEN-1-YL]-3-PROPYLTHIOPHEN-2(5H)-ONE'>TLJ</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_I Beta-ketoacyl-[acyl-carrier-protein] synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c70 OCA], [https://pdbe.org/4c70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c70 RCSB], [https://www.ebi.ac.uk/pdbsum/4c70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c70 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c70 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c70 RCSB], [http://www.ebi.ac.uk/pdbsum/4c70 PDBsum]</span></td></tr>
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</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4c70" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium sp. h37rv]]
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[[Category: Large Structures]]
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[[Category: Bommineni, G R]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Fekete, A]]
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[[Category: Bommineni GR]]
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[[Category: Kapilashrami, K]]
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[[Category: Fekete A]]
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[[Category: Kisker, C]]
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[[Category: Kapilashrami K]]
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[[Category: Mueller, M J]]
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[[Category: Kisker C]]
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[[Category: Schaefer, C M]]
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[[Category: Mueller MJ]]
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[[Category: Schiebel, J]]
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[[Category: Schaefer CM]]
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[[Category: Tonge, P J]]
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[[Category: Schiebel J]]
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[[Category: Condensing enzyme]]
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[[Category: Tonge PJ]]
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[[Category: Kas enzyme]]
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[[Category: Mycolic acid synthesis]]
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[[Category: Thiolactomycin]]
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[[Category: Transferase]]
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[[Category: Type 2 fatty acid biosynthesis]]
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Current revision

Crystal structure of M. tuberculosis C171Q KasA in complex with TLM4

PDB ID 4c70

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