4bqh

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==Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor==
==Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor==
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<StructureSection load='4bqh' size='340' side='right' caption='[[4bqh]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4bqh' size='340' side='right'caption='[[4bqh]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4bqh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BQH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4bqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BQH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9VU:(3S)-3-[2-(1,3-BENZODIOXOL-5-YL)-2-OXIDANYLIDENE-ETHYL]-4-BROMANYL-5-METHYL-3-OXIDANYL-1H-INDOL-2-ONE'>9VU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9VU:(3S)-3-[2-(1,3-BENZODIOXOL-5-YL)-2-OXIDANYLIDENE-ETHYL]-4-BROMANYL-5-METHYL-3-OXIDANYL-1H-INDOL-2-ONE'>9VU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bqh RCSB], [http://www.ebi.ac.uk/pdbsum/4bqh PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqh OCA], [https://pdbe.org/4bqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bqh RCSB], [https://www.ebi.ac.uk/pdbsum/4bqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bqh ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q386Q8_TRYB2 Q386Q8_TRYB2]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4bqh" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: UDP-N-acetylglucosamine diphosphorylase]]
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[[Category: Fang W]]
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[[Category: Fang, W]]
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[[Category: Raimi OG]]
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[[Category: Raimi, O G]]
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[[Category: VanAalten DMF]]
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[[Category: VanAalten, D M.F]]
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[[Category: Inhibitor]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor

PDB ID 4bqh

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