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2oqf

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[[Image:2oqf.jpg|left|200px]]
 
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{{Structure
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==Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A==
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|PDB= 2oqf |SIZE=350|CAPTION= <scene name='initialview01'>2oqf</scene>, resolution 2.30&Aring;
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<StructureSection load='2oqf' size='340' side='right'caption='[[2oqf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2oqf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQF FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XX1:N~6~-7H-PURIN-6-YL-L-LYSINE'>XX1</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqf OCA], [https://pdbe.org/2oqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqf RCSB], [https://www.ebi.ac.uk/pdbsum/2oqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oq/2oqf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oqf ConSurf].
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<div style="clear:both"></div>
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'''Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A'''
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2OQF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQF OCA].
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__TOC__
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[[Category: Pancreatic ribonuclease]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Bos taurus]]
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[[Category: Boerema, D J.]]
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[[Category: Large Structures]]
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[[Category: He, C.]]
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[[Category: Boerema DJ]]
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[[Category: Kent, S B.H.]]
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[[Category: He C]]
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[[Category: Tereshko, V A.]]
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[[Category: Kent SBH]]
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[[Category: Zhang, J L.]]
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[[Category: Tereshko VA]]
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[[Category: hydrolase]]
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[[Category: Zhang JL]]
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[[Category: non-natural amino acid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:03:09 2008''
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Current revision

Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A

PDB ID 2oqf

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