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2oqk

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[[Image:2oqk.gif|left|200px]]
 
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{{Structure
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==Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A==
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|PDB= 2oqk |SIZE=350|CAPTION= <scene name='initialview01'>2oqk</scene>, resolution 1.80&Aring;
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<StructureSection load='2oqk' size='340' side='right'caption='[[2oqk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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<table><tr><td colspan='2'>[[2oqk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQK FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= cgd8_3330 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5807 Cryptosporidium parvum])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqk OCA], [https://pdbe.org/2oqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqk RCSB], [https://www.ebi.ac.uk/pdbsum/2oqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqk ProSAT]</span></td></tr>
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</table>
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'''Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A'''
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== Function ==
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[https://www.uniprot.org/uniprot/Q5CVP1_CRYPI Q5CVP1_CRYPI] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.[RuleBase:RU004365]
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2OQK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQK OCA].
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Check<jmol>
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[[Category: Cryptosporidium parvum]]
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<jmolCheckbox>
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[[Category: Single protein]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oq/2oqk_consurf.spt"</scriptWhenChecked>
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[[Category: Altamentova, S.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Arrowsmith, C H.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Bochkarev, A.]]
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</jmolCheckbox>
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[[Category: Brokx, S J.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oqk ConSurf].
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[[Category: Dong, A.]]
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<div style="clear:both"></div>
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[[Category: Edwards, A M.]]
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__TOC__
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[[Category: Hassanali, A.]]
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</StructureSection>
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[[Category: Hui, R.]]
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[[Category: Cryptosporidium parvum Iowa II]]
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[[Category: Kozieradzki, I.]]
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[[Category: Large Structures]]
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[[Category: Lew, J.]]
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[[Category: Altamentova S]]
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[[Category: Lin, L.]]
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[[Category: Arrowsmith CH]]
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[[Category: Qiu, W.]]
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[[Category: Bochkarev A]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Brokx SJ]]
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[[Category: Sundstrom, M.]]
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[[Category: Dong A]]
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[[Category: Vedadi, M.]]
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[[Category: Edwards AM]]
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[[Category: Wasney, G.]]
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[[Category: Hassanali A]]
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[[Category: Weigelt, J.]]
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[[Category: Hui R]]
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[[Category: Zhao, Y.]]
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[[Category: Kozieradzki I]]
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[[Category: SO4]]
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[[Category: Lew J]]
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[[Category: cryptosporidium parvum]]
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[[Category: Lin L]]
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[[Category: eukaryotic initiation factor (eif)]]
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[[Category: Qiu W]]
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[[Category: malaria]]
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[[Category: Sundstrom M]]
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[[Category: sgc]]
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[[Category: Vedadi M]]
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[[Category: structural genomic]]
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[[Category: Wasney G]]
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[[Category: structural genomics consortium]]
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[[Category: Weigelt J]]
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[[Category: Zhao Y]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:03:11 2008''
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Current revision

Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A

PDB ID 2oqk

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