2mxb
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the transmembrane domain of the mouse erythropoietin receptor== | |
| + | <StructureSection load='2mxb' size='340' side='right'caption='[[2mxb]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2mxb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MXB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxb OCA], [https://pdbe.org/2mxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mxb RCSB], [https://www.ebi.ac.uk/pdbsum/2mxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mxb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EPOR_MOUSE EPOR_MOUSE] Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.<ref>PMID:8382775</ref> <ref>PMID:8617735</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Erythropoietin receptor|Erythropoietin receptor]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Kang | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| + | [[Category: Kang C]] | ||
| + | [[Category: Lee M]] | ||
| + | [[Category: Li Q]] | ||
| + | [[Category: Wong Y]] | ||
Current revision
Structure of the transmembrane domain of the mouse erythropoietin receptor
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Categories: Large Structures | Mus musculus | Kang C | Lee M | Li Q | Wong Y
