4rze

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'''Unreleased structure'''
 
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The entry 4rze is ON HOLD until Paper Publication
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==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant==
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<StructureSection load='4rze' size='340' side='right'caption='[[4rze]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
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Authors: Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4rze]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RZE FirstGlance]. <br>
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Description: Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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[[Category: Fengwei, L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rze OCA], [https://pdbe.org/4rze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rze RCSB], [https://www.ebi.ac.uk/pdbsum/4rze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rze ProSAT]</span></td></tr>
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[[Category: Xuyang, T]]
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</table>
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[[Category: Yuan, L]]
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== Function ==
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[[Category: Anzhong, L]]
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[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
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[[Category: Tianwei, L]]
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== References ==
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[[Category: Hangzi, C]]
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<references/>
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[[Category: Li, L]]
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__TOC__
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[[Category: Qiao, W]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Anzhong L]]
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[[Category: Fengwei L]]
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[[Category: Hangzi C]]
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[[Category: Li L]]
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[[Category: Qiao W]]
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[[Category: Tianwei L]]
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[[Category: Xuyang T]]
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[[Category: Yuan L]]

Current revision

Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant

PDB ID 4rze

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OCA

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