5aek
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the human SENP2 C548S in complex with the human SUMO1 K48M F66W== | |
| + | <StructureSection load='5aek' size='340' side='right'caption='[[5aek]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5aek]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AEK FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aek OCA], [https://pdbe.org/5aek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aek RCSB], [https://www.ebi.ac.uk/pdbsum/5aek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aek ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SENP2_HUMAN SENP2_HUMAN] Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway (By similarity).<ref>PMID:12192048</ref> <ref>PMID:11896061</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[SUMO 3D Structures|SUMO 3D Structures]] | |
| - | + | *[[Sentrin-specific protease|Sentrin-specific protease]] | |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Castillo V]] |
| - | [[Category: Papaleo | + | [[Category: Espargaro A]] |
| - | [[Category: | + | [[Category: Gallego P]] |
| - | [[Category: | + | [[Category: Grana-Montes R]] |
| - | [[Category: | + | [[Category: Lange R]] |
| + | [[Category: Lindorff-Larsend K]] | ||
| + | [[Category: Papaleo E]] | ||
| + | [[Category: Reverter D]] | ||
| + | [[Category: Torrent J]] | ||
| + | [[Category: Ventura S]] | ||
Current revision
Crystal structure of the human SENP2 C548S in complex with the human SUMO1 K48M F66W
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