2xkr

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==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS CYP142: A NOVEL CHOLESTEROL OXIDASE==
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<StructureSection load='2xkr' size='340' side='right' caption='[[2xkr]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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==Crystal Structure of Mycobacterium tuberculosis CYP142: A novel cholesterol oxidase==
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<StructureSection load='2xkr' size='340' side='right'caption='[[2xkr]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XKR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XKR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.601&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xkr RCSB], [http://www.ebi.ac.uk/pdbsum/2xkr PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xkr OCA], [https://pdbe.org/2xkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xkr RCSB], [https://www.ebi.ac.uk/pdbsum/2xkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xkr ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CP142_MYCTU CP142_MYCTU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/2xkr_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/2xkr_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xkr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2xkr" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Large Structures]]
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[[Category: Driscoll, M]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Lafite, P]]
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[[Category: Driscoll M]]
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[[Category: Levy, C W]]
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[[Category: Lafite P]]
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[[Category: Leys, D]]
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[[Category: Levy CW]]
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[[Category: Mast, N]]
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[[Category: Leys D]]
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[[Category: Mclean, K J]]
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[[Category: Mast N]]
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[[Category: Munro, A W]]
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[[Category: McLean KJ]]
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[[Category: Pikuleva, I A]]
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[[Category: Munro AW]]
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[[Category: Rigby, S E.J]]
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[[Category: Pikuleva IA]]
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[[Category: Oxidoreductase]]
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[[Category: Rigby SEJ]]

Current revision

Crystal Structure of Mycobacterium tuberculosis CYP142: A novel cholesterol oxidase

PDB ID 2xkr

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