4xuu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "4xuu" [edit=sysop:move=sysop])
Current revision (00:55, 28 December 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 4xuu is ON HOLD
+
==The hSac2 domain from human phosphoinositide phosphatase Sac2==
 +
<StructureSection load='4xuu' size='340' side='right'caption='[[4xuu]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4xuu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XUU FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xuu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xuu OCA], [https://pdbe.org/4xuu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xuu RCSB], [https://www.ebi.ac.uk/pdbsum/4xuu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xuu ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SAC2_HUMAN SAC2_HUMAN] Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Hydrolyzes phosphatidylinositol 4,5-bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation.<ref>PMID:11274189</ref> <ref>PMID:17322895</ref>
-
Authors: Hsu, F, Mao, Y
+
==See Also==
-
 
+
*[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]]
-
Description: The hSac2 domain from human phosphoinositide phosphatase Sac2
+
*[[Phosphoinositide phosphatase|Phosphoinositide phosphatase]]
-
[[Category: Unreleased Structures]]
+
== References ==
-
[[Category: Hsu, F, Mao, Y]]
+
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Hsu F]]
 +
[[Category: Mao Y]]

Current revision

The hSac2 domain from human phosphoinositide phosphatase Sac2

PDB ID 4xuu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4xuu"
Personal tools