3j9b

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'''Unreleased structure'''
 
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The entry 3j9b is ON HOLD until Paper Publication
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==Electron cryo-microscopy of an RNA polymerase==
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<SX load='3j9b' size='340' side='right' viewer='molstar' caption='[[3j9b]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3j9b]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/goose/Guangdong/1/1996(H5N1)) Influenza A virus (A/goose/Guangdong/1/1996(H5N1))], [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/goose/Guangdong/3/1997(H5N1)) Influenza A virus (A/goose/Guangdong/3/1997(H5N1))] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J9B FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j9b OCA], [https://pdbe.org/3j9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j9b RCSB], [https://www.ebi.ac.uk/pdbsum/3j9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j9b ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q91R78_9INFA Q91R78_9INFA] Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.[HAMAP-Rule:MF_04063]
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Authors: Chang, S.H., Sun, D.P., Liang, H.H., Wang, J., Li, J., Guo, L., Wang, X.L., Guan, C.C., Boruah, B.M., Yuan, L.M., Feng, F., Yang, M.R., Wojdyla, J., Wang, J.W., Wang, M.T., Wang, H.W., Liu, Y.F.
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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Description: Electron cryo-microscopy of an RNA polymerase
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__TOC__
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[[Category: Unreleased Structures]]
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</SX>
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[[Category: Sun, D.P]]
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[[Category: Large Structures]]
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[[Category: Chang, S.H]]
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[[Category: Synthetic construct]]
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[[Category: Wang, M.T]]
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[[Category: Boruah BM]]
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[[Category: Wang, J.W]]
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[[Category: Chang SH]]
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[[Category: Yang, M.R]]
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[[Category: Feng F]]
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[[Category: Wojdyla, J]]
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[[Category: Guan CC]]
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[[Category: Li, J]]
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[[Category: Guo L]]
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[[Category: Wang, X.L]]
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[[Category: Li J]]
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[[Category: Liu, Y.F]]
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[[Category: Liang HH]]
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[[Category: Wang, H.W]]
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[[Category: Liu YF]]
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[[Category: Feng, F]]
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[[Category: Sun DP]]
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[[Category: Guo, L]]
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[[Category: Wang HW]]
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[[Category: Guan, C.C]]
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[[Category: Wang J]]
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[[Category: Boruah, B.M]]
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[[Category: Wang JW]]
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[[Category: Wang, J]]
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[[Category: Wang MT]]
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[[Category: Liang, H.H]]
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[[Category: Wang XL]]
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[[Category: Yuan, L.M]]
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[[Category: Wojdyla J]]
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[[Category: Yang MR]]
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[[Category: Yuan LM]]

Current revision

Electron cryo-microscopy of an RNA polymerase

3j9b, resolution 4.30Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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