3x1x
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Ras-related protein Rap1B with GppNHp== | |
| + | <StructureSection load='3x1x' size='340' side='right'caption='[[3x1x]], [[Resolution|resolution]] 1.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3x1x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X1X FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x1x OCA], [https://pdbe.org/3x1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x1x RCSB], [https://www.ebi.ac.uk/pdbsum/3x1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x1x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RAP1B_RAT RAP1B_RAT] GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Ikegami | + | [[Category: Rattus norvegicus]] |
| - | [[Category: Park | + | [[Category: Ikegami T]] |
| - | [[Category: Tame | + | [[Category: Noguchi H]] |
| - | [[Category: Unzai | + | [[Category: Park SY]] |
| + | [[Category: Tame JRH]] | ||
| + | [[Category: Unzai S]] | ||
Current revision
Ras-related protein Rap1B with GppNHp
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