This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2poy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:06, 30 August 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2poy.jpg|left|200px]]
 
-
{{Structure
+
==Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A==
-
|PDB= 2poy |SIZE=350|CAPTION= <scene name='initialview01'>2poy</scene>, resolution 1.800&Aring;
+
<StructureSection load='2poy' size='340' side='right'caption='[[2poy]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[2poy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II] and [https://en.wikipedia.org/wiki/Tolypocladium_inflatum Tolypocladium inflatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POY FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
|GENE= cgd2_4120 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 Cryptosporidium parvum Iowa II])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2poy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poy OCA], [https://pdbe.org/2poy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2poy RCSB], [https://www.ebi.ac.uk/pdbsum/2poy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2poy ProSAT]</span></td></tr>
-
 
+
</table>
-
'''Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/A3FQA7_CRYPI A3FQA7_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2POY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POY OCA].
+
Check<jmol>
-
[[Category: Cryptosporidium parvum iowa ii]]
+
<jmolCheckbox>
-
[[Category: Single protein]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poy_consurf.spt"</scriptWhenChecked>
-
[[Category: Arrowsmith, C H.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Artz, J D.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Bochkarev, A.]]
+
</jmolCheckbox>
-
[[Category: Edwards, A M.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2poy ConSurf].
-
[[Category: Hassanali, A.]]
+
<div style="clear:both"></div>
-
[[Category: Hills, T.]]
+
__TOC__
-
[[Category: Hui, R.]]
+
</StructureSection>
-
[[Category: Kozieradzki, I.]]
+
[[Category: Cryptosporidium parvum Iowa II]]
-
[[Category: Lew, J.]]
+
[[Category: Large Structures]]
-
[[Category: Lin, Y H.]]
+
[[Category: Tolypocladium inflatum]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Schapira, M.]]
+
[[Category: Artz JD]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Bochkarev A]]
-
[[Category: Weigelt, J.]]
+
[[Category: Edwards AM]]
-
[[Category: Wernimont, A K.]]
+
[[Category: Hassanali A]]
-
[[Category: Xiao, T.]]
+
[[Category: Hills T]]
-
[[Category: Zhao, Y.]]
+
[[Category: Hui R]]
-
[[Category: cryptosporidium]]
+
[[Category: Kozieradzki I]]
-
[[Category: cyclophilin]]
+
[[Category: Lew J]]
-
[[Category: cyclosporin]]
+
[[Category: Lin YH]]
-
[[Category: parvum]]
+
[[Category: Schapira M]]
-
[[Category: sgc]]
+
[[Category: Sundstrom M]]
-
[[Category: structural genomic]]
+
[[Category: Weigelt J]]
-
[[Category: structural genomics consortium]]
+
[[Category: Wernimont AK]]
-
 
+
[[Category: Xiao T]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:15:48 2008''
+
[[Category: Zhao Y]]

Current revision

Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A

PDB ID 2poy

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2poy"
Personal tools