This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4opn
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of mouse glyoxalase I complexed with mAH== | ==Crystal structure of mouse glyoxalase I complexed with mAH== | ||
| - | <StructureSection load='4opn' size='340' side='right' caption='[[4opn]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='4opn' size='340' side='right'caption='[[4opn]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4opn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OPN OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4opn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OPN FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZBF:L-GAMMA-GLUTAMYL-N-(3-ETHYNYLPHENYL)-N-HYDROXY-L-GLUTAMINYLGLYCINE'>ZBF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZBF:L-GAMMA-GLUTAMYL-N-(3-ETHYNYLPHENYL)-N-HYDROXY-L-GLUTAMINYLGLYCINE'>ZBF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4opn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4opn OCA], [https://pdbe.org/4opn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4opn RCSB], [https://www.ebi.ac.uk/pdbsum/4opn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4opn ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/LGUL_MOUSE LGUL_MOUSE] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity). |
| + | |||
| + | ==See Also== | ||
| + | *[[Glyoxalase 3D structures|Glyoxalase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Yuan | + | [[Category: Mus musculus]] |
| - | [[Category: Zhai | + | [[Category: Yuan M]] |
| - | [[Category: Zhang | + | [[Category: Zhai J]] |
| - | [[Category: Zhang | + | [[Category: Zhang H]] |
| - | + | [[Category: Zhang L]] | |
| - | + | ||
Current revision
Crystal structure of mouse glyoxalase I complexed with mAH
| |||||||||||
Categories: Large Structures | Mus musculus | Yuan M | Zhai J | Zhang H | Zhang L
