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4y61
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4y61 is ON HOLD Authors: Yamgata, A., Sato, Y., Goto-Ito, S., Uemura, T. , Maeda, A., Shiroshima, T., Yoshida, T., Fukai, S. Description: [[Catego...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1== | |
| + | <StructureSection load='4y61' size='340' side='right'caption='[[4y61]], [[Resolution|resolution]] 3.36Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4y61]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y61 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.358Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y61 OCA], [https://pdbe.org/4y61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y61 RCSB], [https://www.ebi.ac.uk/pdbsum/4y61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y61 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PTPRD_MOUSE PTPRD_MOUSE] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Selective binding between pre- and postsynaptic adhesion molecules can induce synaptic differentiation. Here we report the crystal structure of a synaptogenic trans-synaptic adhesion complex between Slit and Trk-like family member 2 (Slitrk2) and receptor protein tyrosine phosphatase (RPTP) delta. The structure and site-directed mutational analysis revealed the structural basis of splicing-dependent adhesion between Slitrks and type IIa RPTPs for inducing synaptic differentiation. | ||
| - | + | Structure of Slitrk2-PTPdelta complex reveals mechanisms for splicing-dependent trans-synaptic adhesion.,Yamagata A, Sato Y, Goto-Ito S, Uemura T, Maeda A, Shiroshima T, Yoshida T, Fukai S Sci Rep. 2015 May 19;5:9686. doi: 10.1038/srep09686. PMID:25989451<ref>PMID:25989451</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: | + | <div class="pdbe-citations 4y61" style="background-color:#fffaf0;"></div> |
| - | [[Category: Fukai | + | |
| - | [[Category: | + | ==See Also== |
| - | [[Category: | + | *[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: Uemura | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Fukai S]] | ||
| + | [[Category: Goto-Ito S]] | ||
| + | [[Category: Maeda A]] | ||
| + | [[Category: Sato Y]] | ||
| + | [[Category: Shiroshima T]] | ||
| + | [[Category: Uemura T]] | ||
| + | [[Category: Yamgata A]] | ||
| + | [[Category: Yoshida T]] | ||
Current revision
Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1
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Categories: Large Structures | Mus musculus | Fukai S | Goto-Ito S | Maeda A | Sato Y | Shiroshima T | Uemura T | Yamgata A | Yoshida T
