4wsu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:55, 28 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 3'SLN==
==The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 3'SLN==
-
<StructureSection load='4wsu' size='340' side='right' caption='[[4wsu]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+
<StructureSection load='4wsu' size='340' side='right'caption='[[4wsu]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4wsu]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WSU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WSU FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4wsu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus Influenza A virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WSU FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wsr|4wsr]], [[4wss|4wss]], [[4wst|4wst]], [[4wsv|4wsv]], [[4wsw|4wsw]], [[4wsx|4wsx]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wsu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wsu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wsu RCSB], [http://www.ebi.ac.uk/pdbsum/4wsu PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wsu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wsu OCA], [https://pdbe.org/4wsu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wsu RCSB], [https://www.ebi.ac.uk/pdbsum/4wsu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wsu ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A0A0J9X246_9INFA A0A0J9X246_9INFA] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 15: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4wsu" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Carney, P J]]
+
[[Category: Influenza A virus]]
-
[[Category: Chang, J C]]
+
[[Category: Large Structures]]
-
[[Category: Stevens, J]]
+
[[Category: Carney PJ]]
-
[[Category: Villanueva, J M]]
+
[[Category: Chang JC]]
-
[[Category: Yang, H]]
+
[[Category: Stevens J]]
-
[[Category: H6]]
+
[[Category: Villanueva JM]]
-
[[Category: Hemagglutinin]]
+
[[Category: Yang H]]
-
[[Category: Influenza virus]]
+
-
[[Category: Viral protein]]
+

Current revision

The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 3'SLN

PDB ID 4wsu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4wsu"
Personal tools