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2qvh

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[[Image:2qvh.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)==
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|PDB= 2qvh |SIZE=350|CAPTION= <scene name='initialview01'>2qvh</scene>, resolution 1.76&Aring;
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<StructureSection load='2qvh' size='340' side='right'caption='[[2qvh]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=OSB:2-SUCCINYLBENZOATE'>OSB</scene>
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<table><tr><td colspan='2'>[[2qvh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca_YX Thermobifida fusca YX]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVH FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
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|GENE= Tfu_1410 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=269800 Thermobifida fusca YX])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OSB:2-SUCCINYLBENZOATE'>OSB</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvh OCA], [https://pdbe.org/2qvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvh RCSB], [https://www.ebi.ac.uk/pdbsum/2qvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2qvh TOPSAN]</span></td></tr>
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</table>
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'''Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)'''
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== Function ==
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[https://www.uniprot.org/uniprot/MENC_THEFY MENC_THEFY] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444). Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substrate (PubMed:24872444).<ref>PMID:24060347</ref> <ref>PMID:24872444</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2QVH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca_yx Thermobifida fusca yx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVH OCA].
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Check<jmol>
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[[Category: Single protein]]
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<jmolCheckbox>
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[[Category: Thermobifida fusca yx]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvh_consurf.spt"</scriptWhenChecked>
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[[Category: Burley, S K.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Sugadev, R.]]
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</jmolCheckbox>
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[[Category: Swaminathan, S.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qvh ConSurf].
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[[Category: MG]]
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<div style="clear:both"></div>
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[[Category: OSB]]
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== References ==
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[[Category: 9312b]]
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<references/>
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[[Category: lyase]]
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__TOC__
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[[Category: new york structural genomix research consortium]]
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</StructureSection>
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[[Category: nysgxrc]]
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[[Category: Large Structures]]
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[[Category: o-succinylbenzoate]]
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[[Category: Thermobifida fusca YX]]
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[[Category: protein structure initiative]]
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[[Category: Burley SK]]
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[[Category: psi-ii]]
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[[Category: Sugadev R]]
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[[Category: structural genomic]]
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[[Category: Swaminathan S]]
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[[Category: tim barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:29:57 2008''
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Current revision

Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)

PDB ID 2qvh

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