4q2f
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Galectin-1 in Complex with Ligand AN020== | |
| + | <StructureSection load='4q2f' size='340' side='right'caption='[[4q2f]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4q2f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q2F FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2XW:PROP-2-EN-1-YL+2-(ACETYLAMINO)-4-O-(3-O-{[1-(5-AMINO-1H-1,2,4-TRIAZOL-3-YL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}-BETA-D-GALACTOPYRANOSYL)-2-DEOXY-BETA-D-GLUCOPYRANOSIDE'>2XW</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q2f OCA], [https://pdbe.org/4q2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q2f RCSB], [https://www.ebi.ac.uk/pdbsum/4q2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q2f ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Galectin 3D structures|Galectin 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Bertleff-Zieschang | + | __TOC__ |
| - | [[Category: Grimm | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bertleff-Zieschang N]] | ||
| + | [[Category: Grimm C]] | ||
Current revision
Galectin-1 in Complex with Ligand AN020
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