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4hti

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==Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin==
==Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin==
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<StructureSection load='4hti' size='340' side='right' caption='[[4hti]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4hti' size='340' side='right'caption='[[4hti]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HTI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hti]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HTI FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPRN2, KIAA0387 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.954&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hti OCA], [https://pdbe.org/4hti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hti RCSB], [https://www.ebi.ac.uk/pdbsum/4hti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hti ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hti OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hti RCSB], [http://www.ebi.ac.uk/pdbsum/4hti PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PTPR2_HUMAN PTPR2_HUMAN]] Implicated in development of nervous system and pancreatic endocrine cells.<ref>PMID:8878534</ref> <ref>PMID:8798755</ref>
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[https://www.uniprot.org/uniprot/PTPR2_HUMAN PTPR2_HUMAN] Implicated in development of nervous system and pancreatic endocrine cells.<ref>PMID:8878534</ref> <ref>PMID:8798755</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4hti" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
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*[[Tyrosine phosphatase|Tyrosine phosphatase]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Large Structures]]
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[[Category: Ermacora, M R]]
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[[Category: Ermacora MR]]
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[[Category: Jakoncic, J]]
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[[Category: Jakoncic J]]
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[[Category: Noguera, M E]]
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[[Category: Noguera ME]]
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[[Category: Poskus, E]]
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[[Category: Poskus E]]
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[[Category: Autoimmunity]]
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[[Category: Diabetes]]
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[[Category: Ferredoxin-like fold]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Ia-2beta]]
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[[Category: Phogrin]]
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[[Category: Protein-tyrosine phosphatase]]
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[[Category: Receptor]]
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[[Category: Transmembrane protein]]
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Current revision

Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin

PDB ID 4hti

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